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Bioinformatics of Genome Regulation and Structure II

Bioinformatics of Genome Regulation and Structure II
Catalogue Information
Field name Details
Dewey Class 572.865 (DDC 22)
Title Bioinformatics of Genome Regulation and Structure II ([Ebook]) / edited by Nikolay Kolchanov, Ralf Hofestaedt, Luciano Milanesi.
Added Personal Name Hofestaedt, Ralf
Milanesi, Luciano
Kolchanov, N. A.
Other name(s) SpringerLink (Online service)
Publication Boston, MA : Springer , 2006
Physical Details : v.: digital
ISBN 9780387294551
Summary Note The last 15 years in development of biology were marked with accumulation of unprecedentedly huge arrays of experimental data. The information was amassed with exclusively high rates due to the advent of highly efficient experimental technologies that provided for high throughput genomic sequencing; of functional genomics technologies allowing investigation of expression dynamics of large groups of genes using expression DNA chips; of proteomics methods giving the possibility to analyze protein compositions of cells, tissues, and organs, assess the dynamics of the cell proteome, and reconstruct the networks of protein-protein interactions; and of metabolomics, in particular, high resolution mass spectrometry study of cell metabolites, and distribution of metabolic fluxes in the cells with a concurrent investigation of the dynamics of thousands metabolites in an individual cell. Analysis, comprehension, and use of the tremendous volumes of experimental data reflecting the intricate processes underlying the functioning of molecular genetic systems are unfeasible in principle without the systems approach and involvement of the state-of-the-art information and computer technologies and efficient mathematical methods for data analysis and simulation of biological systems and processes. The need in solving these problems initiated the birth of a new science- postgenomic bioinformatics or systems biology in silic0:
System details note Online acccess to this digital book is restricted to subscription institutions through IP address (only for SISSA internal users)
Internet Site http://dx.doi.org/10.1007/0-387-29455-4
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Catalogue Information 22003 Beginning of record . Catalogue Information 22003 Top of page .

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