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A Guide to Numerical Modelling in Systems Biology

A Guide to Numerical Modelling in Systems Biology
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Dewey Class 515.352
Title A Guide to Numerical Modelling in Systems Biology ([EBook]) / by Peter Deuflhard, Susanna Röblitz.
Author Deuflhard, Peter
Added Personal Name Röblitz, Susanna author.
Other name(s) SpringerLink (Online service)
Publication Cham : : Springer International Publishing : : Imprint: Springer, , 2015.
Physical Details X, 168 p. 42 illus., 33 illus. in color. : online resource.
Series Texts in computational science and engineering 1611-0994 ; ; 12
ISBN 9783319200590
Summary Note This book is intended for students of computational systems biology with only a limited background in mathematics. Typical books on systems biology merely mention algorithmic approaches, but without offering a deeper understanding. On the other hand, mathematical books are typically unreadable for computational biologists. The authors of the present book have worked hard to fill this gap. The result is not a book on systems biology, but on computational methods in systems biology. This book originated from courses taught by the authors at Freie Universität Berlin. The guiding idea of the courses was to convey those mathematical insights that are indispensable for systems biology, teaching the necessary mathematical prerequisites by means of many illustrative examples and without any theorems. The three chapters cover the mathematical modelling of biochemical and physiological processes, numerical simulation of the dynamics of biological networks, and identification of model parameters by means of comparisons with real data. Throughout the text, the strengths and weaknesses of numerical algorithms with respect to various systems biological issues are discussed. Web addresses for downloading the corresponding software are also included.  .:
Contents note Preface -- Outline -- ODE Models for Systems Biological Networks -- Numerical Simulation of ODE Models -- Parameter Identification in ODE Models -- Appendix -- Software -- Index.
System details note Online access to this digital book is restricted to subscription institutions through IP address (only for SISSA internal users).
Internet Site http://dx.doi.org/10.1007/978-3-319-20059-0
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